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[D-Pro2,D-Phe7,D-Trp9]-Substance P
CAS No. 77275-70-8
[D-Pro2,D-Phe7,D-Trp9]-Substance P( ——— )
Catalog No. M41635 CAS No. 77275-70-8
[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name[D-Pro2,D-Phe7,D-Trp9]-Substance P
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NoteResearch use only, not for human use.
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Brief Description[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.
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Description[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.
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In Vitro[D-Pro2,D-Phe7,D-Trp9] Substance P (10-100 μM; 2 min or 10 min) produces dose-related contractions of the guinea-pig ileum and in the rabbit external jugular vein.
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In Vivo[D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorSubstance P
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Research Area———
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Indication———
Chemical Information
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CAS Number77275-70-8
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Formula Weight1476.82
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Molecular FormulaC72H105N19O13S
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hawcock AB, et al. Agonist effects of D-Pro2,D-Phe7,D-Trp9substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80(1):135-8.?
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